Aytakin Huseynli’s research bridges political science and social policy, offering insights into family and child well-being outcomes. She examines how socio-political factors shape child and family well-being, with a particular focus on child wealth, health, education, and violence against children and family members. She also analyzes the effect of fossil fuel wealth on social development and how the resource curse impacts marginalized populations in fossil-extracting nations, where abundant wealth often hinders development. She proposes evidence-based solutions to improve child and family well-being, particularly feasible in contexts that lack the political will and accountability including countries that are rich in oil-gas-minerals. She collaborates with senior policymakers and global organizations to design and implement social policies. 

Huseynli is a founder of the national association of social workers in Azerbaijan including social work profession and education. She was instrumental in social policies and services for disadvantaged children and families in Former Soviet Union nations. 

She published in Child Abuse and Neglect, the British Journal of Social Work, Child Indicators Research, and Children and Youth Services Review.  She serves on the Editorial Board of the journal International Social Work and International Journal of School Social Work. She is actively involved in global social development through UNICEF, the International Federation of Social Workers, the International Council on Social Welfare, the International Consortium on Social Development, and Social Services in the Context of Conflict Network.